- Garland, former CEO of Portola Pharmaceuticals, to take the helm as PACT’s CEO
- Leadership transition supports PACT’s clinical and corporate progress


**South San Francisco, Calif., March 5, 2021 –** PACT Pharma, Inc., a clinical-stage company pioneering individualized, non-viral precision genome engineered, tumor-specific T cell therapies for the treatment of patients with solid tumors, today announced the appointment of Scott Garland as Chief Executive Officer. Mr. Garland assumes the CEO role effective today, succeeding Alex Franzusoff, Ph.D., who will be staying with the company through mid-year in an advisory role to support the transition. 

“With its cell therapy in clinical trials, PACT is working to rapidly bring its personalized adoptive T cell therapies to patients in need,” said Blake Byers, Ph.D., chairman of PACT’s board and general partner at GV. “As the company’s pipeline progresses, we are committed to adding key competencies to our longstanding strengths in research and development, and Scott’s experience leading the commercial launches of multiple novel therapies will be important for PACT. We thank Alex for his many contributions to the company over the last four years, particularly in guiding the company into clinical development, and wish him the best in his retirement.” 

Mr. Garland was formerly CEO of Portola Pharmaceuticals, which was acquired by Alexion in 2020 for $1.4 billion. At Portola, he led the company through the commercial launch of Andrexxa®, a novel reversal agent for factor Xa inhibitors. Before joining Portola, Mr. Garland held leadership roles at multiple pharmaceutical and biotechnology companies. At Relypsa, he served first as chief commercial officer, then as president overseeing the U.S. commercial launch of Veltassa® for the treatment of hyperkalemia. Prior to Relypsa, Mr. Garland spent three years as chief commercial officer at Exelixis where he built the company’s commercial organization, transitioning Exelixis from a development-stage to a commercial-stage company with the launch of cabozantinib in medullary thyroid cancer. He also spent nine years at Genentech, where he led the commercial franchises for two multi-billion dollar therapies – Avastin® and Rituxan®. Mr. Garland received a Bachelor of Science degree from California Polytechnic State University-San Luis Obispo and a Master’s degree in business administration from the Fuqua School of Business at Duke University.

“I am honored and privileged to join PACT – and its world class team – at this important moment in the company’s growth,” said Mr. Garland. “PACT is well positioned to be a leader in developing personalized anti-cancer T cell therapies against solid tumors. I appreciate the work that Alex has done to build PACT into a clinical-stage biotechnology company and I am delighted at the opportunity to help the company in its efforts to advance cell therapies to benefit patients with solid tumors.”   

“I am very proud of the landmark achievements and progress that the PACT team has made over the past four years in advancing our personalized adoptive T cell therapies, including launching our current clinical program across multiple solid tumor types,” said Dr. Franzusoff. “I am confident that the company is in excellent hands under Scott’s leadership.” 

**About PACT Pharma**

PACT Pharma is a clinical-stage biopharmaceutical company pioneering individualized, non-viral precision genome engineered, tumor-specific T cell therapies for the treatment of patients with solid tumors. PACT Pharma is now enrolling patients in its first-in-human Phase 1 clinical trial. Each person's cancer emerges with a private signature of mutations. PACT Pharma identifies these cancer mutation targets (neoantigens) for each person, biochemically verifies and captures T cells from their blood and uses its proprietary, cutting edge (non-viral) precision genome engineering technologies to manufacture a personalized immune cell therapy product for each person with cancer.



**Media Contact**

Sarah Sutton
Finsbury Glover Hering (FGH)
sarah.sutton@fgh.com
202-337-0808

**Investor Contact**

Uneek Mehra
umehra@pactpharma.com



PACT Pharma Announces Planned Retirement of CEO Alex Franzusoff, Veteran Biotech Executive Scott Garland Named as Successor

Press Releases

**South San Francisco – January 11, 2021** – PACT Pharma, Inc., a clinical-stage company developing transformational personalized neoTCR-T cell therapies for the eradication of solid tumors, today announced that the company will present at the 39th Annual J.P. Morgan Healthcare Conference, which is being held virtually, on January 11, 2021 at 7:30 a.m. PT/10:30 a.m. ET.  

**About PACT Pharma**

PACT is a clinical-stage biopharmaceutical company pioneering individualized, non-viral precision genome engineered, tumor-specific T cell therapies for the treatment of patients with solid cancers. PACT is now enrolling patients in its first-in-human Phase 1 clinical trial. 

Each person's cancer emerges with a private signature of mutations. PACT identifies these cancer mutation targets (neoantigens) for each person, biochemically verifies and captures T cells from their blood and uses its proprietary, cutting edge (non-viral) precision genome engineering technologies to manufacture a personalized immune cell therapy product for each person with cancer.

For more information please visit[ www.pactpharma.com]( www.pactpharma.com). 


**Media Contact**

Sarah Sutton
Finsbury Glover Hering (FGH)
[ssutton@fgh.com](mailto:ssutton@fgh.com) 
202-337-0808

**Investor Contact**

Uneek Mehra
[umehra@pactpharma.com](mailto:umehra@pactpharma.com)


PACT Pharma to Present at the 39th Annual J.P. Morgan Healthcare Conference

- The round was led by Vida Ventures, a next generation life science venture firm with industry-leading experience in cell and gene therapy  
- The financing will be used to expand clinical & manufacturing development to deliver clinical data for patients with multiple solid tumor types  

SOUTH SAN FRANCISCO, Calif., Jan. 10, 2020 /PRNewswire/ — PACT Pharma, in pursuit of its vision to eradicate solid tumors using transformational, first-in-class fully personalized NeoTCR-T cell therapies, today announced that it has closed an oversubscribed $75 million Series C financing. This round, led by Vida Ventures, a next generation life science venture firm with industry-leading experience in the cell and gene therapy, also included current investors of PACT.  

Combined with proceeds from previous financings, PACT will use the Series C proceeds to expand the scope of its clinical plan to investigate NeoTCR-T cell products targeting multiple neoantigens for a spectrum of solid tumor types. In addition to clinical expansion, PACT will open in 2020 a next-gen GMP manufacturing facility in South San Francisco to support the end-to-end production and supply chain for the engineering of personalized neoantigen-targeted autologous T cells. Under the direction of industry veteran Tim Moore, President and Chief Technology Officer, PACT will leverage the new in-house manufacturing facility to automate manufacturing and analytic processes to reduce cycle time and manufacturing costs.  

“PACT has grown from company launch to opening its first-in-kind clinical trial in two years. Our progress has been exhilarating and the support from our existing investors has made that progress possible,” said Alex Franzusoff, PhD, Chief Executive Officer of PACT Pharma. “As we look to the next stage of our development and expansion of our clinical programs, we are excited to have interest from a new group of prominent investors who both understand the potential of NeoTCR-T cell therapy and have direct experience in the space. Vida Ventures stood out as a partner of choice, given their depth of operational experience in research, clinical development and manufacturing in cell therapy as well as their proven ability to guide companies like Kite and Allogene across key stages of development.  

As part of the Series C financing, Helen S. Kim, Managing Director at Vida Ventures, will join the Company’s Board of Directors. Ms. Kim brings over 25 years of biotechnology leadership experience and serves on the boards of Assembly Biosciences, Applied Molecular Transport, A2 Biotherapeutics and Exicure, Inc.  

“Our investment in PACT Pharma represents our goal to fund scientific advances by embracing cutting edge innovation with the potential to make a meaningful difference in the lives of patients,” said Kim. “PACT has developed a pioneering platform of personalized designer T cells with the potential to target some of the most elusive solid cancers facing society today.”  

**ABOUT PACT Pharma**  

PACT Pharma is an independent, privately funded clinical stage company, based in South San Francisco, California, developing transformational personalized neoTCR-T cell therapies for the eradication of solid tumors and is now enrolling patients in its first-in-human Phase 1 clinical studies at several key academic centers of the CIRM-funded Alpha Clinic network, in California.  

PACT Pharma’s distinguised co-founders, David Baltimore (Nobel Laureate), Antoni Ribas, Jim Heath, Terry Rosen and Juan Jaen launched the company in early 2017. The company is backed by GV (formerly Google Ventures), Canaan, Casdin Capital, Droia, Foresite Capital, Invus Opportunities, Pontifax and Wu Capital and is supported by investment from AbbVie Ventures and Taiho Ventures. PACT Pharma’s technology is designed to individually program tumor-exclusive targeting into each patient’s own immune system cells to eradicate their own cancer. The process, which is currently in Phase 1 clinical testing, involves taking a biopsy of a person’s cancer tissue to assess the tumor-exclusive mutations with predictive algorithms, then to biologically verify the optimal targets by capturing T cells from blood that already recognize the mutations. Using the T cell receptor information from the captured T cells, together with proprietary, cutting edge, (non-viral) precision genome engineering technologies, fresh patient T cells are edited in one step to craft tumor-specific neoTCR-P1 cells. These private designer T cells have been shown to immediately kill mutation-expressing tumors in pre-clinical studies, and to create a deep reservoir of ‘ready-to-go’ neoTCR-P1 cells with the potential for long term persistence to prevent future cancer recurrence. These developments offer PACT exceptional prospects to leverage the potential of ideal tumor targets and biologically verified neoTCRs into clinical development of neoTCR-T adoptive cell therapies.  

**CONTACT:** William Nevius, wnevius(at)canaan.com

PACT Pharma Raises $75M in Oversubscribed Series C Financing to Develop Fully Personalized NeoTCR-T Cell Therapies for Patients with Cancer

PACT is a company pushing the frontiers of science, technology and medicine. We are creating T cell therapies to alter the course of cancer and meaningfully impact the lives of patients who urgently need breakthrough therapies. We are building a team of driven, talented and passionate individuals committed to bringing these novel personalized therapies to people living with cancer.

Join Us

PACT is a clinical stage immuno-oncology company dedicated to engineering T cell therapies by seeking to harness the inherent biology and curative potential of each patient's immune system to treat their cancer and advance the field of immune-driven medicines.

Who We Are

PACT Pharma is an exciting, well-funded biotechnology company, advancing to clinical studies in 2019 with facilities and laboratories in South San Francisco, CA.&nbsp; PACT Pharma is developing personalized adoptive T cell therapies for the eradication of solid tumors.&nbsp; We are in the San Francisco bay area, in the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including aggressive participation in the growth of the company in the form of stock option grants.&nbsp;PACT Pharma is developing tumor-mutation-targeted T Cells tailored for each patient. Tumor mutation (neoE) targeting is programmed into the patient&rsquo;s own T cells to seek out &amp; kill the tumors. Using (non-viral) precision genome engineering, the neoE-targeted Tcell receptors (TCRs) replace the endogenous TCR of fresh CD8 and CD4 T cells collected from that same patient followed by minimal expansion in closed systems for re-infusion into the patient. These patient-specific neoTCR-P1 cells are formulated to immediately kill all neoantigen-expressing tumors, together with a deep reservoir of &lsquo;ready-to-go&rsquo; neoTCR-P1 cells for long-term persistence and capable of rapid expansion to prevent future cancer recurrence.&nbsp;We are currently recruiting for&nbsp;Sr.&nbsp;Quality Assurance Engineer, reporting to the Director, Quality Assurance. This position will be based in&nbsp;South San Francisco.&nbsp;Responsibilities:The ideal candidate is an experienced QA Engineer with a track record of success in GMP environments and understands biologics and/or cell therapy processes (i.e. cell culture, expansion, fill/finish, aseptic environments, reagent/media control, contamination control). The job incumbent will be responsible for the following in support of QA activities:<ul><li>Provide QA oversight for qualification and validation lifecycle including but not limited to equipment, analytical instrument, process, and cleaning within cGMP environment.</li><li>Draft and revise standard operating procedures (SOPs), qualification &amp; validation-related templates per PACT Pharma's Quality System requirement.</li><li>Review and approve qualification and validation documents including commissioning, Risk Assessment, Qualification and Validation protocols (IQ, OQ, PQ), summary reports, and all related documents as needed to support cGMP manufacturing and QC laboratory systems.</li><li>Resolve and approve qualification and validation discrepancies and deviations.</li><li>Lead Quality initiatives for new cGMP Aseptic product and raw material facility construction.&nbsp;</li><li>Partner and drive implementation for cGMP new equipment management program.&nbsp;</li><li>Implement periodic review process.</li><li>Review Change Control records, as needed.</li><li>Review equipment maintenance and calibration certificates.</li><li>Provide training and guidance on Quality Assurance topics to foster a quality culture and quality mindset.</li><li>Perform compliance review of internal controls and procedures in PACT Pharma&rsquo;s Quality System and ensure alignment with current regulatory requirements.</li><li>Prepare Quality metrics to show the health of PACT&rsquo;s Quality System and make recommendations/improvements in policies and procedures.</li><li>Other functions as necessary for QA under management&rsquo;s discretion and in support of QA systems.</li></ul>Minimal Qualifications:<ul><li>Must have a thorough working knowledge of personal computer systems and desktop office applications, including Word, Excel, and PowerPoint. Excellent verbal and written communication skills.</li><li>Great knowledge of regulatory qualification and validation requirements</li><li>Ability to build strong working relationships with multiple departments.</li><li>The ideal candidate holds a bachelor&rsquo;s degree or higher in relevant biological sciences.</li><li>The role demands a highly goal-driven approach and the ability to focus on time-sensitive objectives.</li><li>Must have worked for 5+ years in the industry with cGMP Quality Assurance experience in a similar environment.&nbsp;</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Corporate (South San Francisco)

Sr. Quality Assurance Validation Engineer

Our next virtual Open House is on&nbsp; September 23, 2021, from 4:45 pm - 6 pm PST. You are invited to our virtual PACT Pharma Open House!&nbsp; &nbsp;This event includes:&nbsp;&nbsp;<ul><li>An introduction to our open positions from our recruiters, how to apply, and what PACT Pharma looks for</li><li>You'll hear from some of our Scientists &amp; RA's about what it's like to work here, info about our technology, and what they love about PACT Pharma</li><li>Our Scientist will bring you on a journey of our science and process.</li><li>We will also answer your questions!</li></ul>Please click on the apply button to submit your CV for your RSVP.&nbsp; If you have any questions you want answered, reply to the automated email and we will make sure to get to them during the event. &nbsp;If you forget, don't worry, we will have a way for you to ask during the Open House with any of our remaining time.&nbsp; &nbsp; We will be emailing you the zoom link and reminders as the date gets closer.&nbsp; Read about our second open house success here -&nbsp;<a href="https://www.linkedin.com/company/pact-pharma-immuno-oncology/posts/?feedView=all&amp;viewAsMember=true">PACT Pharma: Posts | LinkedIn</a>.We look forward to seeing you there!PACT Talent Acquisition&nbsp;Team

Career Open House  next one is September 23, 2021

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient's individual tumor and engineering T cells to kill that specific tumor. In principle, this technology can be used to treat any cancer type.&nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.&nbsp;We are about eradicating cancer, come join our team!&nbsp;We are currently recruiting for a Procurement Manager who will report to the Head of Procurement and continue advancing PACT Pharma&rsquo;s cutting-edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives.&nbsp;What You Will Do:The Procurement Manager will play a lead role in securing the supplies and services that ensure successful process execution for all areas of the company. The procurement team has responsibility for all purchasing activities for PACT Pharma supporting R&amp;D, G&amp;A, and capital investments. The role will be responsible for generating requests for proposals, negotiating quotes with suppliers, placing orders, and ensuring a stable supply of materials and services throughout the organization. This role is located in South San Francisco.Minimal Qualifications:<ul><li>Oversee daily operations of the Procurement function and serve as a hands-on leader that understands and performs the daily tactical and strategic functions</li><li>Negotiate vendor agreements, contracts, and terms</li><li>Work closely with various functions to ensure proper selection, evaluation, and acquisition of all materials while also mitigating critical situations as they arise with the supplier base</li><li>Track and report key functional metrics to reduce expenses and improve the effectiveness</li><li>Identify, develop and drive operational excellence / continuous improvement</li><li>Be the point of contact for invoice reconciliation of accounts payable</li><li>Actively develop and manage vendor performance using key performance indicators and scorecard development, business reviews, and effective contract change/dispute management process</li><li>Collaborate with business owners to develop accurate scopes of work, including gathering product and service specifications; implement supplier management programs to ensure continuous improvement and monitoring</li><li>Provide training and day-to-day support on procurement systems, policy, and processes for the business unit and/or corporate staff involved in purchasing activities</li><li>Manage vendor relationships and be expected to coordinate work with others, both internally and externally</li><li>Support and execute strategic sourcing policies, practices, and systems&nbsp;</li></ul>Preferred Qualifications: <ul><li>Bachelors Science degree with 6+ years of experience, preferably within&nbsp;biotechnology / pharmaceutical industry procurement</li><li>Working knowledge of cGMPs</li><li>An expert in procurement processes and sourcing of goods and services for the pharmaceutical/biotech industry.</li><li>Demonstrated success in improving organizational performance by developing and promoting talent and providing learning and career growth opportunities for team</li><li>Experience with gene or cell therapy is a plus</li><li>Experience working with Point Purchasing and/or ERP systems is a plus</li><li>Ability to work in a small company and high growth, fast-paced environment&nbsp;</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate based on race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Procurement Manager (temporary position)

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.&nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for&nbsp;a Temporary to Hire Cell Therapy Specialists.&nbsp;This position will be based in South San Francisco.&nbsp;Responsibilities:Under the supervision of the Supervisor/ Manager, the Cell Therapy Specialist will have the opportunity to participate in both manufacturing processes of immunotherapy cell products within a GMP environment, with the main focus in Cell Manufacturing. The duties of this position will primarily consist of manufacturing primary human cells including activities such as culture media preparation, culture processing and management, and cryopreservation.&nbsp; Furthermore, you will be responsible for completing successful qualifications and ongoing support procedures for cleanroom operations and assisting in the development, writing, and review of SOPs, material specifications, standard manufacturing procedures, batch records, and other GMP documentation. The ideal candidate must have a collaborative and inquisitive nature, must possess excellent organizational and verbal, and written communication skills, and be flexible in their working hours.&nbsp;&nbsp;<ul><li>Perform required processing required to produce and assess safe and efficacious products</li><li>Proficiently functions within ISO cleanroom environments, ensuring personal and product safety</li><li>Operate with the proper aseptic technique when handling all product and materials</li><li>Consistently produce a high level of documentation accuracy and clarity</li><li>Perform programmed cell operations using specific equipment and closed systems</li><li>Perform cryopreservation of products using controlled-rate freezers</li><li>Proficiently operate and maintain equipment according to designed procedures</li><li>Process products according to established standard operating procedures and batch records</li><li>Work cross-functionally with different groups to support clinical trial studies</li><li>Complete quality records in a timely manner&nbsp;</li></ul>Qualifications:<ul><li>Bachelor&rsquo;s degree or associate degree in a biologics, biotechnology, or related field preferred</li><li>A 2+ years of applicable experience in a clinical laboratory, hematology, blood banking, immunology, or cGMP manufacturing</li><li>Experience in cell culture processing and cleanroom required</li><li>Experience in cell counting and cell selection operation preferred</li><li>Strong work ethic, methodical approach to new challenges</li><li>Must be able to work as a team, as well as independently with minimal supervision</li><li>Demonstrates tact and courtesy in dealing with others</li><li>Excellent organizational skills and attention to detail</li><li>Good verbal and written communication skills</li><li>Skills in Microsoft Office (Excel, Word) preferred</li><li>Able to adapt to company growth and evolving responsibilities</li><li> Ability to work a flexible schedule that may include nights, weekends, and/or holidays</li></ul>Physical Demands:The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of the job. While performing the duties of this job, the employee is frequently required to stand; walk; sit; bend; stretch; use hands to finger, handle or feel; reach with hands and arms, and talk or hear. The employee is regularly required to climb or balance; stoop, kneel, or crouch. The employee is frequently required to lift and/or move up to 30 pounds. Non-absorbent laboratory coats are required, as well as latex (or a non-latex substitute) gloves. When working with potentially hazardous materials that may spray, aerosol, or otherwise contact skin or mucous membranes, face shields or goggles must be worn. Heavy cryo gloves must be used when working with liquid nitrogen.&nbsp;&nbsp;PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Cell Therapy Specialist - Manufacturing (Temp to Hire)

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient's individual tumor and engineering T cells to kill that specific tumor. In principle, this technology can be used to treat any cancer type.&nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.&nbsp;We are about eradicating cancer, come join our team!We are currently recruiting for a Research Associate II who will report to a Scientist and continue advancing PACT Pharma&rsquo;s cutting-edge engineered cell product. This will be a unique opportunity to see your work rapidly translate into the clinic and impact patient lives.The person in this role will be responsible for the processing of clinical blood samples for the identification and isolation of patient private NeoE-specific T cells, as part of product selection for the manufacture of the adoptive cell therapy product (neoTCR-P1) for the patients. This process is performed in a GMP-like laboratory setting and includes flow cytometry, RT-PCR, and Next-generation Sequencing (NGS) analysis of single T cells. The ideal candidate should enjoy operating in an exceptionally dynamic and cooperative environment.What you will Do:<ul><li>The candidate will be utilizing their expertise to construct patient-specific reagent libraries</li><li>The candidate will be using FACS machine to analyze patient blood samples</li><li>The candidate will be carrying out experiments to generate a DNA library for NGS</li><li>The candidate will be analyzing data and writing reports to propose the therapeutic candidates for the patients</li></ul>Minimum Qualifications:<ul><li>The ideal candidate should hold a bachelor&rsquo;s degree or a master&rsquo;s degree in a relevant field, with 1 year of related work or lab experience</li><li>Experience with at least one of FACS experience, RT-PCR, next-generation sequencing (NGS), fluid handling robots</li><li>The candidate should be highly goal-driven and have demonstrated the ability to focus on time-sensitive objectives.</li><li>This position will require flexible work schedules (Shift schedules)&nbsp;</li></ul>Preferred Qualifications (Not Required):<ul><li>Some basic data analysis skills using R, Python, or others</li><li>RNA-seq experience.&nbsp;</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;&nbsp;

Research Associate II, R&D NGS

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.&nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a diverse work family with a dynamic and earnest culture. We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for a Director of Quality Assurance Operations&nbsp;who will report to the Vice President of Quality Assurance and continue advancing PACT Pharma&rsquo;s cutting-edge engineered cell product. This will be a unique opportunity to see your contributions to PACT Pharma&rsquo;s personalized process rapidly translate into the clinic and impact patient lives.&nbsp;What You Will Do:The ideal candidate is an experienced&nbsp;Quality Assurance leader&nbsp;with a track record of success in GMP&nbsp;operations&nbsp;and understands biologics and/or cell therapy processes (i.e. cell culture, expansion, fill/finish, aseptic environments, reagent/media control, contamination control). The job incumbent will be responsible for&nbsp;leading and mentoring QA Operations and Document Control staff that&nbsp;support&nbsp;the following&nbsp;QA activities:&nbsp;&nbsp;<ul><li>Coordinate production and laboratory Quality&nbsp;review for on-time product release.&nbsp;&nbsp;</li><li>Oversee the internal and external audit program, which includes a focus on phase-appropriate cGMP compliance, regulatory agency inspection readiness, and for-cause inspections.&nbsp;</li><li>Recommend GMP clinical phase systems for audit; write audit plans, coordinate scheduling, conduct and write reports to close audits. Follow-up on corrective actions.&nbsp;</li><li>Review GMP quality metrics. Analyze data relating to process controls, and continuous process improvement efforts. Coordinate the necessary quality adjustments.&nbsp;</li><li>Conduct trend analysis of audit results and provide Senior management with initial root cause analysis.&nbsp;</li><li>Review relevant GMP documents for compliance to company SOPs, quality systems, and regulatory requirements.&nbsp;</li><li>Oversee&nbsp;PACT&nbsp;investigations&nbsp;for&nbsp;a nonconforming product, laboratory out-of-specification, and oversight of corrective and preventive action implementation.&nbsp;</li><li>Provide phase appropriate guidance, interpretation, support, training, and input on the interpretation and implementation of regulations, guidelines, company procedures, and policies.&nbsp;</li><li>Participate in or lead teams for special projects as assigned.&nbsp;</li><li>Develop and manage PACT Training program&nbsp;for GXP operations.&nbsp;&nbsp;</li><li>Develop and work with laboratory, manufacturing, facilities, and supply chain staff to implement quality process controls relating to all areas of operation, including the following systems: quality, facilities and equipment, materials management, production, packaging, and labeling.&nbsp;&nbsp;</li></ul>Minimal Qualifications:&nbsp;<ul><li>Prior management experience required.</li><li>Ability to build strong working relationships with multiple departments.</li><li>The ideal candidate holds a bachelor&rsquo;s degree or higher in relevant biological sciences.</li><li>The role demands a goal-driven approach and the ability to focus on time-sensitive objectives.</li><li>Demonstrated understanding through prior experience of GMP regulation and guidelines related to the conduct of good manufacturing practice.&nbsp;</li><li>Must have worked in clinical development as a Quality professional for a minimum of 5+ years and at least 10+ years total in a GMP environment.&nbsp;&nbsp;</li><li>Must have&nbsp;strong&nbsp;writing skills.&nbsp;</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.

Director of Quality Assurance Operations

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for a Research Associate II&nbsp;in the clinical pipeline group to continue advancing PACT Pharma&rsquo;s cutting-edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives.The person in this role will be responsible for evaluation of T cells as part of the product selection process prior to the manufacturing of PACT Pharma's adoptive cell therapy product (neoTCR-P1) for clinical patients. This process is performed in a GMP-like laboratory setting and includes characterizing T cell phenotype and functionality using state-of-the-art flow cytometry-based methods and automation. The ideal candidate should enjoy operating in an exceptionally dynamic and cooperative environment.Responsibilities:<ul><li>The ideal candidate will perform and thoroughly document ex vivo T cell functional assays according to established procedures</li><li>Demonstrate strong accountability, organizational, and inter-personal skills; will collaborate and work effectively within the team and across multi-functional teams</li><li>Identify areas of the process for improvement and work with the process development team to test and implement improvements</li><li>Analyze flow cytometry data and carefully write reports that will help inform product candidate selection in clinical patients</li><li>Operate advanced liquid handling and robotic laboratory automation</li><li>Become a process expert and mentor/train research associates in performing the workflows</li><li>Assist junior team members with issues that may arise, including any necessary documentation</li></ul>Qualifications:<ul><li>Bachelor&rsquo;s degree with 2+ years of industry experience, preferably in a production environment</li><li>The candidate should be proficient in state-of-the-art techniques for characterizing T cell phenotype and measuring T cell functionality (antigen-specific killing assays, cytokine production, proliferation)</li><li>The candidate should be proficient at cell-based bioassays, flow cytometry and/or FACS, primary human T cells and mammalian cell culture</li><li>Must have excellent organizational skills and should be able to communicate clearly and concisely, both verbally and in the form of written reports</li><li>Demonstrated ability to work well within a team environment is a must</li><li>Experience with automated lab workflows and liquid handlers is a plus</li><li>Experience operating within a formal quality management system. cGMP or ISO 13485 production experience is a plus</li><li>This position will require flexible work schedules (Shift schedules)&nbsp;</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Research Associate II - Flow Cytometry

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for a Research Associate in the clinical pipeline group to continue advancing PACT Pharma's cutting-edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives.The person in this role will be responsible for the evaluation of T cells as part of the product selection process prior to the manufacturing of PACT Pharma's adoptive cell therapy product (neoTCR-P1) for clinical patients. This process is performed in a GMP-like laboratory setting and includes characterizing T cell phenotype and functionality using state-of-the-art flow cytometry-based methods and automation. The ideal candidate should enjoy operating in an exceptionally dynamic and cooperative environment.Responsibilities:<ul><li>Perform and thoroughly document ex vivo T cell functional assays according to established procedures</li><li>Collaborate and work effectively within the team and across multi-functional teams</li><li>Identify areas of the process for improvement and work with the process development team to test and implement improvements</li><li>Analyze flow cytometry data and carefully write reports that will help inform product candidate selection in clinical patients</li><li>Operate advanced liquid handling and robotic laboratory automation</li><li>Become a process expert and mentor/train research associates in performing the workflows</li><li>Assist junior team members with issues that may arise, including any necessary documentation</li></ul>Qualifications:<ul><li>Bachelor&rsquo;s degree with 1 + years experience or a master&rsquo;s degree with 1+ year, preferably in a production environment</li><li>Proficient in state-of-the-art techniques for characterizing T cell phenotype and measuring T cell functionality (antigen-specific killing assays, cytokine production, proliferation)</li><li>Proficient at cell-based bioassays, ELISA, flow cytometry/FACS, and primary human T cells and mammalian cell culture</li><li>Must have excellent organizational skills and should be able to communicate clearly and concisely, both verbally and in the form of written reports</li><li>Demonstrated ability to work well within a team environment is a must</li><li>Demonstrate strong accountability, organizational, and interpersonal skills</li><li>Experience with automated lab workflows and liquid handlers is a plus</li><li>Experience operating within a formal quality management system. cGMP or ISO 13485 production experience is a plus</li><li>This position will require flexible work schedules (Shift schedules)&nbsp;</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Research Associate, Flow Cytometry

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.&nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a diverse work family with a dynamic and earnest culture. We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for a Quality Assurance Document Control Specialist&nbsp;who will report to Quality Assurance Manager and continue advancing PACT Pharma&rsquo;s cutting-edge engineered cell product. This will be a unique opportunity to see your contributions to PACT Pharma&rsquo;s personalized process rapidly translate into the clinic and impact patient lives.The ideal candidate is an experienced Documents Specialist with a track record of success in a Life Sciences (GxP) based organization. The job incumbent will be responsible for the generation and maintenance of controlled documentation, logs, and databases in support of GxP Facilities and Operations.&nbsp;&nbsp;What You Will Do:<ul><li>Administer documentation workflows within Master Control, electronic Document Management System (MC-EDMS).</li><li>Administer the scanning, filing, maintenance, and retrieving of hard copy documentation and GxP records.</li><li>Collaborate with Document Change Record (DCR) initiators to ensure accuracy of the change justification and review for changes in MC-EDMS metadata.</li><li>Issue controlled cGMP logbooks, log sheets, Master Batch Record (MBR), and labels to support Facilities, Laboratories, and Manufacturing Operations.</li><li>Coordinate the review and revision of procedures, specifications, and forms, as needed.</li><li>Support the archiving of controlled records for all functional departments.</li><li>Perform other job duties as assigned&nbsp;</li></ul>Qualifications:<ul><li>Bachelor&rsquo;s degree with a minimum of 5 years of quality assurance or equivalent experience</li><li>Experience with MasterControl Electronic Document Management System preferred</li><li>Working knowledge of controlled document process requirements for Life Sciences organizations under GMP requirements</li><li>Solid knowledge of personal computer systems and desktop office applications, including Word, Excel, and PowerPoint</li><li>Experience with key cGMP Quality Systems (e.g. Change management, Deviation, CAPA, Documentation)</li><li>Strong verbal and written communication skills</li><li>Ability to build strong working relationships with multiple departments</li><li>Highly goal-driven approach and the ability to focus on time-sensitive objectives</li><li>Must be able to work independently with minimum supervision</li><li>Strong organizational skills, with the ability to successfully manage multiple priorities&nbsp;</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate based on race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Quality Assurance Document Control Specialist (temp-to-hire)

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.&nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a diverse work family with a dynamic and earnest culture. We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for a Scientist I who will report to the Senior Scientist and continue advancing PACT Pharma&rsquo;s cutting-edge engineered cell product. This will be a unique opportunity to see your contributions to PACT Pharma&rsquo;s personalized process rapidly translate into the clinic and impact patient lives.What You Will Do:The ideal candidate will be responsible for the design and execution of critical path experiments for the discovery of neoepitope-specific TCRs, to be to be used for the manufacture adoptive cell therapeutics (ACT). These experiments will focus on single-cell RNAseq analysis of patient samples and engineered T-cells, including well-based, microfluidic (e.g., 10X), and other approaches. The candidate should have familiarity or proficiency with programming languages (R and/or Python) for data analysis. The ideal candidate should also have a familiarity with RT-PCR, NGS library preparation, and flow cytometry. The ideal candidate should enjoy operating in an exceptionally dynamic and cooperative environment. The position entails both works at the lab bench and computational data analysis.&nbsp;Minimal Qualifications:<ul><li>PhD in a relevant field or a Master&rsquo;s degree with 7+ years experience, with a career focus in immunology, immuno-oncology, or related fields</li><li>Proficiency at single-cell based RNAseq technologies (well-based or 10X-based), data analysis using programming languages (R and/or Python), NGS library preparation, PCR, and RT-PCR</li><li>Additional consideration will be given to candidates with proficiency in FACS, flow cytometry, and other single-cell technology work</li><li>The candidate should be highly goal-driven and have demonstrated the ability to focus on time-sensitive objectives</li><li>Experience with fluid handling robots, T-cell biology, and immune-oncology will be a plus</li><li>Familiarity and/or proficiency in CITE-seq and ATAC-seq methodologies will be a plus</li><li>She/he must have excellent organizational skills and should be able to communicate clearly and concisely, both verbally and in the form of written reports&nbsp;</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate based on race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Scientist I – T cell single-cell analysis and TCR discovery

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.&nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for&nbsp;Senior Cell Therapy Specialists.&nbsp;This position will be based in South San Francisco.&nbsp;Responsibilities:Under the supervision of the Supervisor/ Manager, the Cell Therapy Specialist will have the opportunity to participate in both manufacturing processes of immunotherapy cell products within a GMP environment, with the main focus in Cell Manufacturing. The duties of this position will primarily consist of manufacturing primary human cells including activities such as culture media preparation, culture processing and management, and cryopreservation.&nbsp; Furthermore, you will be responsible for completing successful qualifications and ongoing support procedures for cleanroom operations and assisting in the development, writing, and review of SOPs, material specifications, standard manufacturing procedures, batch records, and other GMP documentation. The ideal candidate must have a collaborative and inquisitive nature, must possess excellent organizational and verbal, and written communication skills, and be flexible in their working hours.&nbsp;&nbsp;<ul><li>Perform required processing required to produce and assess safe and efficacious products</li><li>Proficiently functions within ISO cleanroom environments, ensuring personal and product safety</li><li>Operate with the proper aseptic technique when handling all product and materials</li><li>Consistently produce a high level of documentation accuracy and clarity</li><li>Perform programmed cell operations using specific equipment and closed systems</li><li>Perform cryopreservation of products using controlled-rate freezers</li><li>Proficiently operate and maintain equipment according to designed procedures</li><li>Process products according to established standard operating procedures and batch records</li><li>Work cross-functionally with different groups to support clinical trial studies</li><li>Complete quality records in a timely manner&nbsp;</li></ul>Qualifications:<ul><li>Bachelor&rsquo;s degree or associate degree in a biologics, biotechnology, or related field preferred</li><li>3+ years of applicable experience in a clinical laboratory, hematology, blood banking, immunology, or cGMP manufacturing</li><li>Experience in cell culture processing and cleanroom required</li><li>Experience in cell counting and cell selection operation preferred</li><li>Strong work ethic, methodical approach to new challenges</li><li>Must be able to work as a team, as well as independently with minimal supervision</li><li>Demonstrates tact and courtesy in dealing with others</li><li>Excellent organizational skills and attention to detail</li><li>Good verbal and written communication skills</li><li>Skills in Microsoft Office (Excel, Word) preferred</li><li>Able to adapt to company growth and evolving responsibilities</li><li> Ability to work a flexible schedule that may include nights, weekends, and/or holidays</li></ul>Physical Demands:The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of the job. While performing the duties of this job, the employee is frequently required to stand; walk; sit; bend; stretch; use hands to finger, handle or feel; reach with hands and arms, and talk or hear. The employee is regularly required to climb or balance; stoop, kneel, or crouch. The employee is frequently required to lift and/or move up to 30 pounds. Non-absorbent laboratory coats are required, as well as latex (or a non-latex substitute) gloves. When working with potentially hazardous materials that may spray, aerosol, or otherwise contact skin or mucous membranes, face shields or goggles must be worn. Heavy cryo gloves must be used when working with liquid nitrogen.&nbsp;&nbsp;PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Senior Cell Therapy Specialist - Manufacturing

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for Talent Acquisition Coordinator, reporting to Sr. Manager of Talent Acquisition. This position will be based in South San Francisco.Responsibilities:<ul><li>Assist with various recruiting tasks and processes that include scheduling phone and on-site interviews, assisting with applicant tracking system administration, managing job postings, references checks, and sourcing and greeting candidates.</li><li>Provide a high level of customer service and quality throughout the recruiting process and to internal employees.</li><li>Assist in ongoing process improvement initiatives for Human Resources and Staffing.</li><li>Manage relationships across HR and Staffing, employees, hiring managers, vendors, and candidates/applicants.</li><li>Support Admin staff and function as a backup when needed.</li></ul>Minimal Qualifications:<ul><li>High school degree or GED required with 1 + years of customer service work experience</li><li>Office administrative experience or HR-related experience is a plus.</li><li>Experience with an ATS is a plus</li><li>Experience with managing multiple calendars on Outlook</li><li>Excellent attention to detail.</li><li>Superb multitasking skills.</li><li>Ability to work in a high-growth team environment.</li><li>Stellar interpersonal and communication skills.</li><li>Experience with MS Office Skills (Outlook, Word, Excel, PowerPoint)</li><li>Ability to work in a flexible fast-paced environment to meet the business needs.</li></ul>&nbsp;PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.

Talent Acquisition Coordinator (Temporary 6 - 8 months)

PACT Pharma&nbsp;is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient's individual tumor and engineering T cells to kill that specific tumor.&nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world's premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.&nbsp;We are currently recruiting for a Senior Research Associate in Tumor Immunology&nbsp;who will report to the Scientist and continue advancing PACT Pharma&rsquo;s cutting edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives.&nbsp;What you will do:&nbsp;The person in this role will be responsible for performing immunological assays and contributing to discovery research programs for next-generation T cell therapies for cancer. The candidate should enjoy operating in an exceptionally dynamic and cooperative environment and will collaborate with a larger cross-disciplinary team of immunologists, biologists, engineers, and bio-informaticians.&nbsp;Responsibilities:<ul><li>Perform ex vivo T cell functional assays according to established procedures</li><li>Perform flow cytometry, ELISA, cell culture, and other cell-based assays</li><li>Experience with molecular biology</li><li>Contribute to generating pre-clinical data to support IND filing</li><li>Accurately document experimental procedures and data in electronic lab notebooks</li><li>Analyze and compile data; communicate research findings to the group and company in the form of written reports and/or oral presentations&nbsp;</li></ul>Minimum Qualifications:<ul><li>Bachelor&rsquo;s or Master&rsquo;s degree in Immunology, Cell or Molecular Biology, Genetics, Biology, Biochemistry, or related discipline</li><li>2+ years of experience if holding a master&rsquo;s degree and 3+ years of experience if holding a bachelor&rsquo;s degree</li><li>Experience with culturing primary human cells and/or cell lines</li><li>Experience with flow cytometry, ELISA, and cell-based assays</li><li>Able to follow detailed procedures</li><li>Ability to focus on deliverables and have demonstrated the ability to prioritize time-sensitive objectives</li><li>Adept at working independently and in a collaborative team environment</li><li>Excellent organizational skills and able to communicate clearly and concisely, both verbally and in the form of written reports&nbsp;</li></ul>Preferred Qualifications:<ul><li>Working knowledge of common molecular techniques such as PCR, cloning, RNA extraction and CRISPR/Cas9</li><li>Experience with R/Python and analysis of large scale transcriptomic and epigenetic datasets (e.g. from scRNAseq, ATAC-seq, and/or CITE-seq)</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.

Senior Research Associate -  Tumor Immunology

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.&nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a diverse work family with a dynamic and earnest culture. We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently searching for an Associate Director Laboratory Operations supporting Cell Engineering and will report to the Vice President of Operations. This will be a unique opportunity to design and implement new operational processes and see your contributions to PACT&rsquo;s personalized therapy directly translate into the clinic and impact patient lives.The ideal candidate should be experienced in both production laboratory best practices as well as the latest molecular cloning techniques and mammalian cell culture. She/he will lead this core operations team in implementing robust and scalable procedures as a hands-on player/coach.The candidate should enjoy operating in an exceptionally dynamic and cooperative environment and will communicate results to and coordinate efforts with a larger cross-disciplinary team of immunologists, biologists, engineers, and bio-informaticians.What You Will Do:<ul><li>Lead, mentor, and grow a team of research associates and scientists responsible for generating constructs used to engineer patient-derived T cells</li><li>Serve as the sole point of contact and process owner for the molecular cloning portion of PACT&rsquo;s production pipeline</li><li>Define and implement operational protocols and best practices.</li><li>Manage workflows, materials, and resources to ensure the quality and timely delivery of plasmids</li><li>Oversee processes to identify and implement process improvements focused on quality, turnaround time, and cost</li><li>Collaborate with process development and engineering to scale your operation by automating wherever possible</li><li>Author SOPs and work instructions in accordance with PACT&rsquo;s quality management system and provide data for regulatory documentation to support clinical development</li></ul>Minimal Qualifications:<ul><li>Bachelor&rsquo;s or master&rsquo;s degree with 8+ years experience or Ph.D. with 5+ years industry experience with a career focus in cell or molecular biology, biochemistry, or molecular genetics.</li><li>5+ years experience managing a production laboratory operation</li><li>Extensive hands-on experience with nucleic acid purification, primer design, protein expression, PCR, and standard cloning</li><li>Hands-on experience with mammalian cell culture and sterile technique</li><li>Experience operating within a formal quality management system</li><li>Communicate clearly and concisely, both verbally and in the form of written reports</li><li>Demonstrated ability to implement laboratory best practices, continuous improvement methodologies, and lean manufacturing principles</li><li>Highly goal-driven and have demonstrated the ability to focus on time-sensitive objectives</li></ul>An incumbent with experience in the following areas is a plus:<ul><li>cGMP or ISO 13485 production experience</li><li>Experience in a turnaround time-sensitive production environment</li><li>Experience with liquid handlers/automation equipment</li><li>Experience with complex LIMS, informatics, or data management</li><li>Mammalian cell culture and transfection, ideally primary human T cells</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.

Associate Director, Laboratory Operations, Cell Engineering

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for a Senior Research Associate in the clinical pipeline group to continue advancing PACT Pharma&rsquo;s cutting-edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives.The person in this role will be responsible for evaluation of T cells as part of the product selection process prior to the manufacturing of PACT Pharma's adoptive cell therapy product (neoTCR-P1) for clinical patients. This process is performed in a GMP-like laboratory setting and includes identifying T-cells capable of targeting tumor-specific neoantigens using our imPACT Isolation Technology&reg;. The ideal candidate should enjoy operating in an exceptionally dynamic and cooperative environment.Responsibilities:<ul><li>Process clinical blood samples for the identification and isolation of patient neoE-specific T cells to advance PACT&rsquo;s neoTCR-P1 clinical trial</li><li>Primary patient PBMC handling and FACS of candidate</li><li>Following established protocols, generate NGS library preparation for Illumina sequencing platforms</li><li>Analyze flow cytometry data and NGS data following our existing analysis pipeline</li><li>Carefully write reports that will help inform product candidate selection in clinical patients</li><li>Demonstrate strong accountability, organizational, and interpersonal skills; will collaborate and work effectively within the team and across multi-functional teams</li><li>Identify areas of the process for improvement and work with the process development team to test and implement improvements</li><li>Operate advanced liquid handling and robotic laboratory automation</li><li>Become a process expert and mentor/train research associates in performing the workflows</li><li>Assist junior team members with issues that may arise, including any necessary documentation</li></ul>Qualifications:<ul><li>Bachelor&rsquo;s degree with 4+ or Master&rsquo;s with 2+ years of industry experience, preferably in a production environment</li><li>The candidate should be experienced in handling various cell samples, including primary human T cells, and be proficient with mammalian cell culture work</li><li>Hands-on experience with single-cell technologies, FACS, and NGS library preparation</li><li>Experience with immuno-oncology or T cell biology highly desired</li><li>Must have excellent organizational skills and should be able to communicate clearly and concisely, both verbally and in the form of written reports</li><li>Demonstrated ability to work well within a team environment is a must</li><li>Experience with automated lab workflows and liquid handlers is a plus</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Senior Research Associate, Tumor Immunology

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for a Research Associate I&nbsp;in the clinical pipeline group to continue advancing PACT Pharma&rsquo;s cutting-edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives.The person in this role will be responsible for evaluation of T cells as part of the product selection process prior to the manufacturing of PACT Pharma's adoptive cell therapy product (neoTCR-P1) for clinical patients. This process is performed in a GMP-like laboratory setting and includes identifying T-cells capable of targeting tumor-specific neoantigens using our imPACT Isolation Technology&reg;. The ideal candidate should enjoy operating in an exceptionally dynamic and cooperative environment.Responsibilities:<ul><li>Process clinical blood samples for the identification and isolation of patient neoE-specific T cells to advance PACT&rsquo;s neoTCR-P1 clinical trial</li><li>Primary patient PBMC handling and FACS of candidate</li><li>Following established protocols, generate NGS library preparation for Illumina sequencing platforms</li><li>Analyze flow cytometry data and NGS data following our existing analysis pipeline</li><li>Carefully write reports that will help inform product candidate selection in clinical patients</li><li>Demonstrate strong accountability, organizational, and inter-personal skills; will collaborate and work effectively within the team and across multi-functional teams</li><li>Identify areas of the process for improvement and work with the process development team to test and implement improvements</li><li>Operate advanced liquid handling and robotic laboratory automation</li><li>Become a process expert and mentor/train research associates in performing the workflows</li><li>Assist junior team members with issues that may arise, including any necessary documentation</li></ul>Qualifications:<ul><li>Bachelor&rsquo;s degree with 1+ yrs of industry experience, preferably in a production environment</li><li>The candidate should be experienced in handling various cell samples, including primary human T cells, and be proficient with mammalian cell culture work</li><li>Hands-on experience with single-cell technologies, FACS, and NGS library preparation</li><li>Experience with immuno-oncology or T cell biology highly desired</li><li>Must have excellent organizational skills and should be able to communicate clearly and concisely, both verbally and in the form of written reports</li><li>Demonstrated ability to work well within a team environment is a must</li><li>Experience with automated lab workflows and liquid handlers is a plus</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Research Associate, ImPACT Clinical Pipeline

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for a Research Associate II&nbsp;in the clinical pipeline group to continue advancing PACT Pharma&rsquo;s cutting-edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives.The person in this role will be responsible for evaluation of T cells as part of the product selection process prior to the manufacturing of PACT Pharma's adoptive cell therapy product (neoTCR-P1) for clinical patients. This process is performed in a GMP-like laboratory setting and includes identifying T-cells capable of targeting tumor-specific neoantigens using our imPACT Isolation Technology&reg;. The ideal candidate should enjoy operating in an exceptionally dynamic and cooperative environment.Responsibilities:<ul><li>Process clinical blood samples for the identification and isolation of patient neoE-specific T cells to advance PACT&rsquo;s neoTCR-P1 clinical trial</li><li>Primary patient PBMC handling and FACS of candidate</li><li>Following established protocols, generate NGS library preparation for Illumina sequencing platforms</li><li>Analyze flow cytometry data and NGS data following our existing analysis pipeline</li><li>Carefully write reports that will help inform product candidate selection in clinical patients</li><li>Demonstrate strong accountability, organizational, and interpersonal skills; will collaborate and work effectively within the team and across multi-functional teams</li><li>Identify areas of the process for improvement and work with the process development team to test and implement improvements</li><li>Operate advanced liquid handling and robotic laboratory automation</li><li>Become a process expert and mentor/train research associates in performing the workflows</li><li>Assist junior team members with issues that may arise, including any necessary documentation</li></ul>Qualifications:<ul><li>Bachelor&rsquo;s degree with 2+ yrs of industry experience, preferably in a production environment</li><li>The candidate should be experienced in handling various cell samples, including primary human T cells, and be proficient with mammalian cell culture work</li><li>Hands-on experience with single-cell technologies, FACS, and NGS library preparation</li><li>Experience with immuno-oncology or T cell biology highly desired</li><li>Must have excellent organizational skills and should be able to communicate clearly and concisely, both verbally and in the form of written reports</li><li>Demonstrated ability to work well within a team environment is a must</li><li>Experience with automated lab workflows and liquid handlers is a plus</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Research Associate II, ImPACT Clinical Pipeline

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient's individual tumor and engineering T cells to kill that specific tumor.&nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world's premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.&nbsp;We are currently recruiting for an Associate Scientist who will report to the Director of Tumor Immunology and continue advancing PACT&rsquo;s cutting edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives.&nbsp;What you will do:&nbsp;The person in this role will be responsible for performing immunological assays and contributing to discovery research programs for next-generation T cell therapies for cancer. The candidate should enjoy operating in an exceptionally dynamic and cooperative environment and will collaborate with a larger cross-disciplinary team of immunologists, biologists, engineers, and bio-informaticians.&nbsp;Responsibilities:<ul><li>Perform ex vivo T cell functional assays according to established procedures</li><li>Perform flow cytometry, ELISA, cell culture and other cell-based assays</li><li>Experience with molecular biology</li><li>Contribute to generating pre-clinical data to support IND filing</li><li>Accurately document experimental procedures and data in electronic lab notebooks</li><li>Analyze and compile data; communicate research findings to the group and company in the form of written reports and/or oral presentations&nbsp;</li></ul>Minimum Qualifications:<ul><li>Bachelor&rsquo;s or master&rsquo;s degree in Immunology, Cell or Molecular Biology, Genetics, Biology, Biochemistry, or related discipline</li><li>4+ years of experience if holding a master&rsquo;s degree and 6+ years of experience if holding a bachelor&rsquo;s degree</li><li>Experience with culturing primary human cells and/or cell lines</li><li>Experience with flow cytometry, ELISA, and cell-based assays</li><li>Working knowledge of common molecular techniques such as PCR, cloning, RNA extraction and CRISPR/Cas9</li><li>Able to follow detailed procedures</li><li>Ability to focus on deliverables and have demonstrated the ability to prioritize time-sensitive objectives</li><li>Adept at working independently and in a collaborative team environment</li><li>Excellent organizational skills and able to communicate clearly and concisely, both verbally and in the form of written reports&nbsp;</li></ul>Preferred Qualifications:<ul><li>Experience with R/Python and analysis of large scale transcriptomic and epigenetic datasets (e.g. from scRNAseq, ATAC-seq, and/or CITE-seq)</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Associate Scientist - Tumor Immunology

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient's individual tumor and engineering T cells to kill that specific tumor. In principle, this technology can be used to treat any cancer type.&nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.&nbsp;We are about eradicating cancer, come join our team!&nbsp;We are looking for a seasoned Director, Enterprise Applications Architecture to join our informatics team to help design, build and implement cloud-native systems and data solutions to support PACT&rsquo;s research and clinical operations. The ideal candidate will have extensive cloud technology experience architecting scalable applications, implementing systems integration and deploying advance analytics solutions including data ingestion, data storage, data visualization, and machine learning.&nbsp;What You Will Do:<ul><li>Work with senior leadership to achieve overall information systems and technology vision and transition from our current state to the end state architecture</li></ul><ul><li>Lead the design, development, and operation of a data analytics platform for data analyst and AI/ML scientists</li><li>Architect system integration strategy by employing system integration platforms and/or web services and APIs</li><li>Lead the strategy and execution around data lifecycle management, data standards, analytics infrastructure</li><li>Support engineering and infrastructure teams with by deploying and enhancing CI/CD pipelines</li><li>Build relationships with stakeholders to understand scientific needs and ensure common understanding of strategy and objectives</li></ul><ul><li>Explore, evaluate and recommend emerging technology trends</li><li>Lead and manage technical data architecture assessment for company‐wide initiatives</li><li>Develop and maintain standards, including but not limited to: system standards, operational standards, software installation and configuration standards</li><li>Coach and mentor team members on software architecture knowledge gaps</li></ul>Minimal Qualifications:<ul><li>BS/MS in computer science, engineering discipline</li><li>7+ years&rsquo; experience in a similar role of enterprise architect or software lead</li></ul><ul><li>Track record of successfully delivering technology solutions to address complex scientific data or informatics challenges with broad impact</li><li>Expert understanding of cloud technologies in AWS, GCP platforms</li></ul><ul><li>Experience with system integration platforms like MuleSoft, Dell Boomi</li><li>Experience with deploying and managing large-scale data on a cloud platform like S3 data lake, Snowflake, Databricks to support data science and ML</li><li>Experience with deploying distributed real-time and batch computing, include big data technologies such as Spark, Hadoop, Hive, Presto, AWS Batch</li><li>Experience architecting MVC based web applications with frameworks like Spring, Node.js, pub / sub and streaming frameworks</li><li>Experience developing and deploying containerized applications with Java, Python or similar languages</li><li>Solid understanding of ETL, relational and NoSQL databases</li><li>Ability to communicate and work effectively, supporting various business departments</li><li>Expert ability to document and present architectural proposals/plans</li><li>Domain knowledge in pharmaceutical and biotech industry is a big plus</li></ul>&nbsp;PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate based on race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.

Director, Enterprise Applications Architecture

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient's individual tumor and engineering T cells to kill that specific tumor. In principle, this technology can be used to treat any cancer type.If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are about eradicating cancer, come join our team!We are currently recruiting for a Quality Control Associate I who will report to the QC Manager and continue advancing PACT&rsquo;s cutting edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives.The QC Associate is responsible for performing testing following written procedure for personalized human T cell therapy product release, stability, and process development.&nbsp; As member of the QC team, the QC Associate contributes to the laboratory operations systems and creating and implementing laboratory operations systems and procedures, to assure the QC laboratory complies with all regulatory requirements.Responsibilities:<ul><li>Maintain rigor and high quality of execution and documentation complying with all regulations</li><li>Conduct work in accordance with guidelines and requirements established by FDA Good Manufacturing Practices, Code of Federal Regulations, and other regulatory agencies</li><li>Draft and review of protocols, SOPs, batch records and regulatory documentation to support clinical development with conciseness in both verbal and written formats</li><li>Identify and troubleshoot equipment problems</li></ul>Qualifications:<ul><li>Bachelor&rsquo;s degree in biological sciences or related field of study with 1+ years of experience in related field</li><li>Experience in pharmaceutical or biotechnology industry laboratory or in an academic laboratory. Preferred to have hands on experience with molecular biology and immunological analytical methods, such as ELISA, gel electrophoresis, or flow cytometry.&nbsp;</li><li>Ability to operate in an exceptionally dynamic and cooperative environment that is goal-driven to achieve time-sensitive objectives.</li><li>Ability to communicate clearly and concisely, both verbally and in the form of written reports, laboratory notebooks, and batch records.&nbsp;</li></ul><h4>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status</h4>

Quality Control Associate I

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.&nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.&nbsp;We are seeking an Associate Director of Program Management to work in this exciting new area of cancer immunotherapy.&nbsp; This individual will work closely with Cross-functional Project Teams &amp; Functional Heads towards achieving corporate &amp; project goals by providing top-notch program management expertise.&nbsp; This position will guide development programs through key development milestones, decision points, and be responsible for the maintenance of project plans while helping PACT employees navigate through organizational change.&nbsp; This is a visible role that will interact with the full range of functions within our rapidly growing company.&nbsp; This position will report to the Director, Program Management responsible for overseeing the R&amp;D projects at PACT and will be based in South San Francisco.&nbsp;What you will do:&nbsp;The Associate Director of Program Management will be responsible for working closely with PACT&rsquo;s Development Leadership to provide both tactical and strategic leadership of the company's development programs and regulatory initiatives. Ideal candidates will demonstrate strength in communication and team leadership to succeed in a role that is highly cross-functional and broadly engaged across the organization. They will bring strong drug development experience and the ability to build and deploy PM tools and best practices to ensure the successful execution of PACT&rsquo;s portfolio in a rapidly growing organization. The Associate Director of Program Management will guide development programs through key development milestones, decision points, and be responsible for the maintenance of project plans while helping PACT employees navigate through organizational change.&nbsp; &nbsp;&nbsp;Key responsibilities will include:&nbsp;<ul><li>Partner with Senior Functional Leaders to manage cross-functional project teams, establish project goals and milestones, and establish the development path for PACT clinical-stage programs and Translational Research activities</li><li>Drive collaboration and coordination across business functions to facilitate the planning process, establishment of goals &amp; milestones, and creation &amp; maintenance of comprehensive timelines that integrate available resources, dependencies, budget, priorities, and other constraints as appropriate</li><li>Create and maintain comprehensive timelines that integrate available resources, dependencies, budget, priorities, and other constraints as appropriate</li><li>Manage timelines and deliverables with the Regulatory subteam, responsible for tracking deliverables for regulatory submissions and key regulatory interactions and ensuring on-time submissions</li><li>Assist in planning clinical and regulatory development strategy and identify realistic and achievable milestones for PACT programs</li><li>Ensure project plans and objectives are clearly established and communicated; Collaborate with and/or manage other Program Managers to integrate timelines and deliverables with the overall project plans</li><li>Develop &amp; maintain PM tools to track overall team progress including project dashboards for Senior Functional Leadership distribution that tracks KPIs</li><li>Collaborate with and/or assist other Program Managers to develop integrated timelines and timeline visualizations</li><li>Manage external development partners, CMOs, CROs, and other key collaborators as required&nbsp;</li></ul>Qualifications:<ul><li>BS/MS with 8+ years progressive project / program management experience in biotech/pharma/diagnostic/device industry along with relevant biologic / pharma / diagnostic / device / drug development background</li><li>One or more years experience leading clinical-stage programs and supporting regulatory filings; Late-stage development / BLA filing experience a plus</li><li>Track record of success leading development programs from preclinical and clinical phases of development through FDA approval and launch</li><li>Demonstration of strategic thinking and high-level planning with the ability to navigate comfortably in an ambiguous and fast-paced environment; ability to operate at both strategic and tactical levels</li><li>Ability to build strong partnerships with internal and external key stakeholders and hold oneself and others accountable for commitments in a productive and collaborative manner</li><li>Business acumen and solid relationship management skills with a focus on cross-functional collaboration and customer service</li><li>Solid understanding of the FDA, EMA, ICH, and other guidelines relevant to the pharmaceutical industry</li><li>Proactive problem solver able to promote ideas persuasively and build on the ideas of others in a constructive manner</li><li>Command of tools to efficiently communicate complex ideas to a wide array of audiences by providing project summaries to Senior Leadership and updates for the wider company to ensure alignment across disciplines and departments</li><li>Positive attitude and ability to foster the qualities of a high performing team through organizational change management</li><li>Experience with biological products, especially cellular therapies, or cancer immunotherapies</li><li>Understanding of immunology, clinical trial execution, GxP requirements, next-generation sequencing, technical logistics, and data infrastructure needs&nbsp;</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Associate Director, Program Management

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team. We are a diverse work family with a dynamic and earnest culture. We are a rapidly expanding, innovative, and collaborative workforce driving towards one main goal, eradicating cancer!We are in the San Francisco Bay Area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for a Scientist I who will play a pivotal role in advancing PACT&rsquo;s cutting-edge engineered cell product. This will be a unique opportunity to see your contributions to PACT&rsquo;s personalized process rapidly translate into the clinic and impact patient lives.What You Will Do:Our team&rsquo;s goal is to assess the success of our engineered T cells in our clinical trial patients, identifying signatures of cell activation and tumor engagement. The ideal candidate will be responsible for the design and execution of critical path experiments for the discovery and analysis of cells expressing neoepitope-specific TCRs. These experiments will focus on the single-cell analysis of patient samples and engineered T-cells, including well-based, microfluidic droplet (e.g., 10X), and other approaches. We currently employ scRNA-seq methods and in the future will add CITE-seq/Ab-seq capabilities. The candidate should have familiarity with scRNA-seq data analysis methods (in R and/or Python). The ideal candidate should also have experience performing RT-PCR, NGS library preparation, and flow cytometry. He or she should enjoy operating in an exceptionally dynamic and cooperative environment, working at the lab bench and bioinformatic terminal.Desired Qualifications:<ul><li>D. in a relevant field or a Master&rsquo;s degree with 4+ years industry experience, with a career focus in immunology, single-cell analysis NGS methods, cell biology, cancer biology, bioengineering, immuno-oncology, systems biology, or related fields</li><li>Proficiency in one or more single-cell RNAseq technologies (10X, plate-seq/well-based, i.e., SMART-seq), CITE-seq, NGS assays, custom library prep design, and Illumina sequencing</li><li>Single-cell bioinformatic analysis using R or Python</li><li>Additional consideration will be given to candidates with proficiency in FACS and flow cytometry</li><li>Standard molecular biology methods and assay development experience</li><li>The candidate should be highly goal-driven and have demonstrated the ability to focus on time-sensitive objectives</li><li>She/he must have excellent organizational skills and should be able to communicate clearly and concisely, both verbally and in the form of written reports</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate based on race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Scientist I –Translational Research, Single-cell Analysis

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team. We are a diverse work family with a dynamic and earnest culture. We are a rapidly expanding, innovative, and collaborative workforce driving towards one main goal, eradicating cancer!We are in the San Francisco Bay Area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for a Scientist II who will play a pivotal role in advancing PACT&rsquo;s cutting-edge engineered cell product. This will be a unique opportunity to see your contributions to PACT&rsquo;s personalized process rapidly translate into the clinic and impact patient lives.What You Will Do:Our team&rsquo;s goal is to assess the success of our engineered T cells in our clinical trial patients, identifying signatures of tumor engagement. Your findings will be critical to guiding the clinical and next-generation development programs.The candidate will develop multi-omic NGS methods to analyze T cells from patients. For example, the candidate will independently design and carry out plate-based NGS analysis of single cells stained with barcoded antibodies. Candidates would have experience or relevant know-how with scRNA-seq, CITE-seq (or other Ab-seq), and/or plate-seq (i.e., SMART-seq). The candidate would also be able to identify and apply bioinformatic tools and packages, for example, to project single-cell multi-omics data onto a reference T cell dataset.The candidate should enjoy operating in an exceptionally dynamic and cooperative environment, frequently tag-teaming with colleagues on other priority projects. The position entails both work at the lab bench and data analysis.Desired Qualifications:<ul><li>D. in a relevant field plus 2+ years of post-doc experience, Ph.D. in a relevant field plus 1+ years of industry experience, or a Master&rsquo;s degree with 7+ years experience, with a career focus in immunology, single-cell analysis NGS methods, cell biology, cancer biology, bioengineering, immuno-oncology, systems biology, or related fields</li><li>Single-cell bioinformatic analysis using R or Python, able to identify or write any necessary analysis methods</li><li>Proficiency in single-cell RNAseq technologies (10X, plate-seq/well-based, i.e., SMART-seq), CITE-seq, NGS assays, custom library prep design, and Illumina sequencing</li><li>Additional strong consideration will be given to candidates with proficiency in FACS and flow cytometry</li><li>Standard molecular and cell biology methods.</li><li>Experience in T-cell biology and immune-oncology</li><li>The candidate should be highly goal-driven and have demonstrated the ability to focus on time-sensitive objectives</li><li>She/he must have excellent organizational skills and should be able to communicate clearly and concisely, both verbally and in the form of written reports</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate based on race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.

Scientist II –Translational Research, T Cell Characterization and Discovery

PACT Pharma&nbsp;is an exciting, well-funded clinical stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.&nbsp;In principle, this technology can be used to treat any cancer type.&nbsp;If you desire a stimulating fast paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.&nbsp;We are currently searching for a&nbsp;Process Development Scientist who will report to the Director of Process Development within our TCR discovery and validation group.The ideal candidate should be creative and interdisciplinary with practical problem-solving skills and hands-on experience in one or more of the following areas: &nbsp;cell biology, flow cytometry, PCR, or next-generation sequencing.This will be a unique opportunity to improve and operationalize PACT&rsquo;s cutting-edge personalized TCR discovery process and see our clinical pipeline through to commercial launch while having a direct impact on patient lives.&nbsp;Responsibilities:&nbsp;<ul><li>Develop, qualify, and implement processes that improve key operational metrics including robustness, reliability, turn-around-time, quality, and cost</li><li>Develop and optimize robust characterization assays using a variety of assay formats and technologies</li><li>Work in collaboration with R&amp;D, bioinformatics, software engineering, automation engineering, QA, and production to develop and deploy high-throughput laboratory automation and software solutions with thorough process controls</li><li>Identify projects, draft proposals, and communicate the feasibility of proposed solutions</li><li>Apply Quality-by-Design principles to define robust, integrated control strategies</li><li>Lead troubleshooting efforts using recognized tools to ensure high production pipeline availability and continuous quality</li></ul>Qualifications:<ul><li>B.S., M.S. or Ph.D. degree in cell or molecular biology, bioengineering, or other relevant biological sciences or engineering disciplines</li><li>8+ (B.S. degree), 5+ (M.S. degree), or 2+ (Ph.D. degree) years industry experience developing assays for use in production workflows</li><li>Ability to propose new projects, design proof of concept experiments, and lead the execution and analysis of the work</li><li>Hands-on experience with workflow development for one or more of the following:&nbsp; cell culture and handling, PCR, flow cytometry, and NGS</li><li>Experience carrying out process characterization to identify and control sources of variability using designed experiments and statistical tools</li><li>Experience in systematic troubleshooting and root cause analysis in a production environment using recognized tools</li><li>Experience developing and characterizing the performance of analytical and functional test methods to ensure quality</li><li>Experience designing and executing validation plans for equipment, processes, and test methods</li><li>Experience developing processes that interface with a LIMS system to manage data capture and analysis</li><li>Highly goal-driven with a demonstrated ability to effectively prioritize and focus on time-sensitive objectives</li><li>Experience operating within a formal quality management system such as CLIA, ISO 13485, or CFR 211</li><li>Ability to communicate clearly and concisely, both verbally and in the form of written reports</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Process Development Scientist, Flow Cytometry

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor. &nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.  We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer! &nbsp;&nbsp;We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants. &nbsp;&nbsp;We are currently recruiting for a Scientist I, Gene Editing who will report to the Associate Director of Laboratory&nbsp;Operations and&nbsp;continue advancing PACT Pharma&rsquo;s cutting edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives.  The individual will be responsible for the execution of high-throughput gene-editing platforms and methods which will be utilized for next-generation T cell therapies. Molecular construct design, validation, data analysis, and regulatory report generation will be key components of your work.&nbsp;&nbsp;The position involves a considerable amount of bench work in a GMP-like environment executing protocols&nbsp;and authoring SOPs to support our clinical&nbsp;operations. The ideal candidate should have keen attention to detail, be highly organized, and should enjoy operating in an exceptionally dynamic and collaborative environment. &nbsp; Responsibilities: &nbsp;<ul><li>Lead 2-3 highly competent RA&rsquo;s and assign work on a daily and weekly basis</li><li>Serve as the technical lead on the&nbsp;gene-editing&nbsp;production operations pipeline and provide scientific guidance to the junior staff</li><li>Implement solutions to operations pipeline bottlenecks</li><li>Resolve quality issues with the production pipeline as and when they arise</li><li>Coordinate and collaborate with other scientists in the team to reduce cycle-time and improve efficiency</li><li> Track and prioritize activities within the&nbsp;gene-editing protein production sub-group</li></ul> Qualifications: &nbsp;<ul><li>Masters with 5+ years of experience in Protein Biochemistry, Molecular&nbsp;Biology, or related disciplines.&nbsp;</li><li>Ph.D. with 2+ years of experience in Protein Biochemistry, Molecular Biology, or related disciplines preferred</li><li>Experience with HTP molecular cloning and molecular construct design is required</li><li>Prior experience with mammalian cell culture is essential</li><li>Acute attention to details, well-organized, diligent with documentation</li><li>Highly goal-driven with the ability to handle delicate experiments in a timely manner</li><li>Able to operate in a collaborative environment and communicate clearly and concisely, both verbally and in the form of written reports</li><li> Experience working with automated platforms</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.  &nbsp;&nbsp;

Scientist, Gene Editing Clinical Pipeline

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.We are currently recruiting for a Research Associate I/II in the NGS Core Group to continue advancing PACT&rsquo;s cutting-edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives.The person in this role will be responsible for supporting multiple projects within the company utilizing next generation sequencing. The ideal candidate should enjoy operating in an exceptionally dynamic and cooperative environment.Responsibilities:<ul><li>Process clinical and/or research samples from nucleic acid extraction to sequencing<ul><li>Following established protocols, perform DNA/RNA extraction from blood or tissue</li><li>Perform RT-PCR</li><li>Generate NGS libraries for Illumina sequencing platforms</li><li>Normalize input, load and run Illumina sequencing instruments</li></ul></li><li>Maintain clean and contamination-free work environment (workspace and instrument cleaning/maintenance)</li><li>Demonstrate strong accountability, organizational, and interpersonal skills; will collaborate and work effectively within the team and across multi-functional teams</li><li>Operate advanced liquid handling and robotic laboratory automation</li><li>Become competent in lab processes and train other research associates in performing the workflows</li></ul>Qualifications:<ul><li>Bachelor&rsquo;s degree with 2+ years of industry experience, preferably in a production environment</li><li>Hands-on experience with nucleic acid extraction from various sources (tissue, blood) and NGS library preparation desired.</li><li>Experience operating and maintaining Illumina sequencing platforms preferred.</li><li>Must have excellent organizational skills and should be able to communicate clearly and concisely, both verbally and in the form of written reports</li><li>Demonstrated ability to work well within a team environment is a must</li><li>Experience with automated lab workflows and liquid handlers is a plus</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.&nbsp;

Research Associate, NGS Core

PACT Pharma&nbsp;is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.&nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.&nbsp; We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!&nbsp;We are in the San Francisco bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.&nbsp;We are currently recruiting for a Senior Quality Control Associate who will help to continue advancing PACT&rsquo;s cutting edge engineered cell product. This will be a unique opportunity to make a direct contribution to bringing novel personalized cell therapies to the clinic and impact patient lives.&nbsp;What you will do: (Responsibilities):The Senior QC Associate is responsible for performing testing following written procedures for personalized DNA vectors and human T cell therapy product release, stability, and process development.&nbsp; As a member of the QC team, the Senior QC Associate contributes to all aspects of the day to day laboratory operations and creating and implementing laboratory operations systems and procedures, to assure the QC laboratory complies with all regulatory requirements.<ul><li>She/he is expected to maintain rigor and high quality of execution and documentation complying with all regulations. Conduct work in accordance with guidelines and requirements established by FDA Good Manufacturing Practices, Code of Federal Regulations, and other regulatory agencies</li><li>She/he must be able to communicate clearly and concisely, both verbally and in the form of written reports, including drafting and review of protocols, SOPs, batch records, and regulatory documentation to support clinical development.</li><li>Identify and troubleshoot technical problems with equipment and analytical procedure.</li><li>Draft and execute analytical procedure qualification/validation protocols and write reports.</li><li>Design and conduct studies to optimize and improve the robustness of analytical procedures.</li></ul>Minimum Qualifications:<ul><li>The ideal candidate should hold a bachelor&rsquo;s degree in biological sciences, biotechnology, or related field of study with 4+ years&rsquo; experience, or hold a Master&rsquo;s degree in Biotechnology or related field of study with 2+ years&rsquo; experience in a similar QC role.</li><li>Highly experienced biological science laboratory professional with in-depth knowledge of flow cytometry&nbsp;methodology for GMP and GLP use, including assay qualification/validation, troubleshooting, panel design, and knowledge of Biomarkers.</li><li>She/he is expected to maintain rigor and high quality of execution and documentation.</li><li>The candidate should enjoy operating in an exceptionally dynamic and cooperative environment that is goal-driven to achieve time-sensitive objectives.</li><li>She/he is highly dedicated to mentor team individuals, motivating team success, and contributing in a collegial manner to the entire company.</li><li>She/he must be able to communicate clearly and concisely, both verbally and in the form of written reports, including drafting and review of protocols, SOPs, batch records, and regulatory documentation to support clinical development.&nbsp;</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.

Senior Quality Control Associate

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient&rsquo;s individual tumor and engineering T cells to kill that specific tumor.  &nbsp;If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.  We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer!  &nbsp;We are in the San Francisco Bay area, the heart of the world&rsquo;s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants.  &nbsp;We are currently recruiting for&nbsp;a Production&nbsp;Engineer&nbsp;specializing in&nbsp;tech transfer and&nbsp;service support for automated systems who will report to the Director of Production Engineering to help to continue advancing PACT&rsquo;s patient-specific product development pipeline. The incumbent should be creative and interdisciplinary with practical problem-solving skills and hands-on experience in the areas of laboratory automation, liquid handling, and instrumentation qualification and validation. This will be a unique opportunity to see your solutions transform the way we process patient samples, improving PACT&rsquo;s throughput and turnaround time, and directly impact patient lives.  &nbsp;What You Will Do: &nbsp;The incumbent will draw on their experience in laboratory automation service and support to maintain and improve automated production processes across a range of scientific disciplines and throughout the company. This individual will need to have experience with liquid handling and laboratory automation principles and be able to identify issues and implementation solutions. He or she will partner closely with scientific subject matter experts as well as automation, software, and process engineers to continue to scale and streamline PACT&rsquo;s processes.  &nbsp;Responsibilities will include: &nbsp;<ul><li>Working on cross-functional teams to develop and improve automated processes&nbsp;&nbsp;</li><li>Performing regular maintenance, calibration, and troubleshooting procedures on liquid handlers, lab equipment, and integrated systems &nbsp;</li><li>Writing and performing verification and validation test protocols and reports including IQ/OQ/PQ&nbsp;</li><li>Performing Operator training&nbsp;</li><li>Improving tools, reporting, and operational documents for tracking spare parts, service calls, and repair decision-making&nbsp;</li></ul>Minimal Qualifications: &nbsp;<ul><li>BS degree in Biology, Chemistry, or similar with a minimum of&nbsp;3&nbsp;years industry experience supporting production laboratory operations&nbsp;</li><li>2&nbsp;+ years of hands-on experience focused on service and support of liquid handlers (Hamilton, Tecan, Beckman, Agilent etc.) and integrated automation solutions&nbsp;</li><li>Familiarity with the principles of continuous process improvement (Lean, Six Sigma, or QbD) &nbsp;</li><li>Experience working in a regulated environment (GxP/CLIA/CAP) &nbsp;</li><li>Highly goal-driven and have demonstrated the ability to effectively prioritize and focus on time-sensitive objectives&nbsp;</li></ul>Preferred Qualifications:  &nbsp;<ul><li>MS or PhD with a minimum of&nbsp;5&nbsp;years of production equipment service support &nbsp;</li><li>Service support experience with integrated systems and multiple liquid handling platforms: Hamilton, Tecan, Beckman, Agilent etc. &nbsp;</li><li>3&nbsp;+ years of experience investigating, developing, and implementing complex laboratory or manufacturing processes&nbsp;&nbsp;</li><li>Experience with instrument integrations and scheduling software&nbsp;&nbsp;</li><li>Experience programming in python, Perl, C#, or similar&nbsp;&nbsp;</li><li>Experience with the principles of continuous process improvement (Lean, Six Sigma, or QbD) &nbsp;</li><li>Experience deploying hardware into production environments with robust validation/verification requirements (cGMP, CLIA, CAP, ISO 13485) and stringent IQ/OQ/PQ   &nbsp;</li><li>Hands-on experience with bacterial and/or mammalian cell culture, protein and nucleic acid purification, microfluidics, and genome engineering platforms (e.g. CRISPR, TALENs). &nbsp;</li></ul>PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status. &nbsp;&nbsp;&nbsp;

Production Engineer

“I joined PACT to work with our impressive management team and innovative technologies to improve cancer therapies. It is the people that make this company exceptional and the mission to cure cancer that motivates me.”

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Rebecca.jpg

Director

"I joined PACT because of the science and the people!  PACT is a special place where people work hard because they are passionate about the science, committed to patients, value teamwork and push the boundaries to never accept the status quo. For those who thrive in a fast paced and innovative environment, PACT provides a rewarding opportunity to tackle challenging projects in a collaborative way."

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Susan.png

Vice President

“I joined PACT Pharma because I was energized by the people and the purpose of the organization and have been continuously impressed by the drive and ambition of the whole team to overcome any challenges. Being encouraged to be authentic with one another, and in all of our work, has really built a strong, unified team. This has been a unique and very rewarding experience for me.”

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Brian_Birdi.jpg

Associate Director

“When I first interviewed at PACT, I remember being impressed by the collaborative and open nature of research within the company. It left quite the impression with me and ultimately guided me towards choosing a career at PACT. Since joining, I am continually grateful for the level of openness and collaboration between teams and departments that is crucial for pioneering scientific work."


Accelerating CurativeT Cell Therapiesfor Cancer

Tailored for Each and Every Person

PACT Pharma Announces Planned Retirement of CEO Alex Franzusoff, Veteran Biotech Executive Scott Garland Named as...

Who We Are

Mission & Vision

Our
Platform

Our
Programs

PACT Voices

Director

Technical Operations

Vice President

Program Management

Associate Director

Automation

Scientist

Tumor Immunology

Join Us

Sr. Quality Assurance Validation Engineer

Career Open House next one is September 23, 2021

Accelerating CurativeT Cell Therapiesfor Cancer

Tailored for Each and Every Person

PACT Pharma Announces Planned Retirement of CEO Alex Franzusoff, Veteran Biotech Executive Scott Garland Named as...

Who We Are

Mission & Vision

OurPlatform

OurPrograms

PACT Voices

Director

Technical Operations

Vice President

Program Management

Associate Director

Automation

Scientist

Tumor Immunology

Join Us

Sr. Quality Assurance Validation Engineer

Career Open House next one is September 23, 2021

Our
Platform

Our
Programs